International Human Subject Research Resources

The external informational resources linked below address important areas for the development, approval, training for and conduct of international human subjects research. Investigators and IRB members may find these resources helpful when considering the multitude of unique and complex issues related to international human subjects research. This list was compiled by the U-M Office of Research Compliance Review (ORCR).

Resources for Developing Programs

The following organizations provide information about International Research Ethics Committee (REC) and IRB standards for accreditation and capacity building:

  • SIDCER(link is external) – The Strategic Initiative for Developing Capacity in Ethical Review (SIDCER) is a network of independently established regional forums for ethical review committees, health researchers, and invited partner organizations with an interest in the development of ethical review.
  • AAHRPP(link is external) – The Association for the Accreditation of Human Research Protection Programs, Inc. (AAHRPP), helps organizations worldwide strengthen their human research protection programs and provides a list of accredited organizations both nationally and internationally.
  • FERCAP(link is external)  Forum for Ethical Review Committees in the Asian and Western Pacific Region (FERCAP), aims to improve understanding and implementation of ethical review for behavioral and biomedical researchers in Asia and the Western Pacific region.
  • CIOMS(link is external) – The Council for International Organizations of Medical Sciences (CIOMS) is an international, non-governmental, non-profit organization established jointly by WHO and UNESCO in 1949.


    These resources represent a compilation of research laws and regulations in most countries in the world along with essential country information that is useful for IRB members who are reviewing studies being conducted abroad.

    • OHRP International Compilation of Human Research Standards(link is external) – Web page containing a downloadable document listing over 1,000 laws, regulations, and guidelines on human subjects protections in over 100 countries and from several international organizations compiled by the HHS Office of Human Research Protections (OHRP).
    • OHRP Compilation of European GDPR Guidances(link is external) – Web page containing links to country-specific documents providing guidance on the European Union’s General Data Protection Regulation (GDPR, 2018) effect on US federally funded human subjects research, including legal, informed consent, and international data transfer guidance.
    • OISE: International Integrity Resources(link is external) – National Science Foundation (NSF) Office of International Science & Engineering (OISE) provides resources to assist in the development of training and oversight plans for the responsible and ethical conduct of research in international contexts and understanding international codes of conduct.
    • World Bank Countries and Economies(link is external) – Comprehensive national data for developing countries around the world; e.g., Agriculture & Rural Development, Aid Effectiveness, Climate Change, Economic Policy & External Debt, Education, Gender, Health, Infrastructure, Labor & Social Protection, Poverty, and more.
    • CIA World Fact Book(link is external) – Provides information on the history, people, government, economy, geography, communications, transportation, military, and transnational issues for 267 world entities.
    • World Health Organization Country Information(link is external) – A webpage listing all the countries that are members of the United Nations and the World Health Organization. Includes population statistics, information on national health systems, mortality, disease burden, and the health profile of each country.


    The International Research Risks Report from ORCR (formerly OHRCR) provides recommendations for mitigating the risks in conducting international human subjects research.

    Note: The articles linked below may require a subscription to a publication database, have a cost to download from that database/website, or require additional software to view. 

    International Ethical Standards and Procedures

    Resources that describe the ethical issues and standards in conducting international research.


    Resources that describe issues related to written consent and alternate consent formats (e.g., oral, pictorial).



    Resources that provide training on the ethical principles, standards, and procedures associated with human subjects research.

    eResearch NextGen: Human Research Application

    OHRP Research Community Forum

    HRPP Policies

    Operations Manual (OM)

    Authorization Agreement Process

    Office of Research Compliance Review (ORCR)

    Single IRB-of Record Process (SIRB)

    Certificate of Confidentiality Process

    HRPP Education Resources

    Information for the Public

    International Research