Resources for Advanced Research Projects Agency for Health (ARPA-H) Applications

About ARPA-H

The newly launched Advanced Research Projects Agency for Health (ARPA-H) supports transformative research to drive biomedical and health breakthroughs – ranging from molecular to societal – to provide transformative health solutions for all. A new component of the U.S. Department of Health and Human Services, ARPA-H is authorized with a budget of $1 billion for Fiscal Year 2023.

The agency works to advance high-potential, high-impact biomedical and health research that cannot be readily accomplished through traditional research or commercial activity.

This new agency released its first Broad Agency Announcement (request for proposals) on March 15, 2023. The proposal process differs from that typically utilized by the National Institutes of Health or other federal agencies and includes two phases: a 3-page abstract followed by a full proposal (if invited).

photo of the US capitol

Open Funding Opportunities

Program Updates

  • New ARPA-H Biomedical Data Fabric Toolbox (BDA): Draft Solicitation 
    • Feedback on the draft solicitation is due by September 20, 2023 to ARPA-H anticipates holding a virtual Proposers’ Day on September 27, 2023. A final solicitation will be posted on September 29, 2023.

Support and Resources for U-M Researchers

Support Teams

The Office of the Vice President for Research is working to aggregate and develop new resources to support teams from across the University of Michigan in their pursuit of ARPA-H funding by:

    • Disseminating timely information on ARPA-H opportunities
    • Providing resources to support faculty in developing successful applications to ARPA-H
    • Identifying program manager candidates from within the U-M research community
    • Creating a network of faculty interested in ARPA-H funding

OVPR’s Office of Research Development can provide proposal management support, including timelines and task lists, drafting supporting documents, editing, and graphic design.

Coaching Programs

OVPR has recruited U-M faculty with strong track records of DARPA support and mentors-in-residence from Innovation Partnerships to serve as peer coaches for researchers seeking ARPA-H funding. There are two coaching options available, and U-M researchers able to apply for one or both:

ARPA-H Programs


Biomedical Data Fabric Toolbox

ARPA-H is seeking proposals to enhance the value extracted from biomedical research data

ARPA-H aims to advance next-generation software tools to synthesize and speed the use of health research data, with early use cases in cancer and a partnership with the National Cancer Institute.

Those interested in applying are encouraged to review the draft solicitation and provide feedback to by September 20, 2023. ARPA-H anticipates holding a virtual Proposers’ Day on September 27, 2023. A final solicitation will be posted on September 29, 2023.


Novel Innovations for Tissue Regeneration in Osteoarthritis 

Novel Innovations for Tissue Regeneration in Osteoarthritis (NITRO) aims to address current issues surrounding osteoarthritis treatment by developing new ways of helping the human body repair its own joints. In particular, the program focuses on three technical areas: injectable bone regeneratives, injectable cartilage regeneratives, and replacement joints built from human cells.

Precision Surgical Interventions

Precision Surgical Interventions (PSI) aims to help all surgical procedures reach their intended goal with no errors and no need for re-operation. The program aims to develop solutions to two major surgical problems: tumor edge visualization and critical anatomy visualization.

ARPA-H Funding

Stay Informed

If you are interested in learning more about ARPA-H, please sign up for the OVPR ARPA-H Listserv.


If you are seeking assistance on an application, please contact, or Lisa Prosser,