National Institutes of Health

The National Institutes of Health partners with researchers across U-M to advance knowledge about the nature and behavior of living systems, and the application of that knowledge to enhance health, lengthen life and reduce illness and disability.

$751 Million

Research Supported by NIH in FY26

2,716

Active Projects Supported by NIH

Melanoma testing could one day be done at home with a skin patch and test strip with two lines, similar to COVID-19 home tests, according to University of Michigan researchers.

Chemical engineering doctoral student Scott Smith places the ExoPatch into a petri dish containing a mouse skin sample to test for melanoma. Image credit: Jeremy Little, Michigan Engineering.

Chemical engineering doctoral student Scott Smith places the ExoPatch into a petri dish containing a mouse skin sample to test for melanoma. Image credit: Jeremy Little, Michigan Engineering.

A new machine-learning-based approach to mapping real-time tumor metabolism in brain cancer patients, developed at the University of Michigan, could help doctors discover which treatment strategies are most likely to be effective against individual cases of glioma.

Illustration depicts a brain with a tumor and its digital twin. The glioma digital twin developed at U-M maps tumor metabolism and could help doctors discover whether a specific drug or diet is likely to slow tumor growth in an individual patient. Image credit: Google Gemini<br />

Illustration depicts a brain with a tumor and its digital twin. The glioma digital twin developed at U-M maps tumor metabolism and could help doctors discover whether a specific drug or diet is likely to slow tumor growth in an individual patient. Image credit: Google Gemini

Unlike most cells in the human body, neurons—the functional cells of our nervous system—cannot typically replace themselves with healthy copies after being damaged.  New research from U-M opens new ways to think about neurodegeneration that could help protect patients against that degradation and neurological decline in the future.

Graphic abstract of the study Pyruvate kinase deficiency links metabolic perturbations to neurodegeneration and axonal protection. Image credit: © 2025 The Author(s), CC 4.0 BY license

Graphic abstract of the study Pyruvate kinase deficiency links metabolic perturbations to neurodegeneration and axonal protection. Image credit: © 2025 The Author(s), CC 4.0 BY license