Natural Sciences
U-M scientists move forward with plans for embryonic stem cell projects
Nov. 4, 2009 is the one-year anniversary of the vote approving Proposal 2, the state constitutional amendment that eased restrictions on human embryonic stem cell research in Michigan. The amendment permits Michigan scientists to derive new human embryonic stem cell lines. While no such projects have begun at U-M, researchers here have taken several significant steps this year to prepare for them. [Read more...]

Hybrid molecules show promise for exploring, treating Alzheimer’s
One of the many mysteries of Alzheimer's disease is how protein-like snippets called amyloid-beta peptides, which clump together to form plaques in the brain, may cause cell death, leading to the disease's devastating symptoms of memory loss and other mental difficulties. In order to answer that key question and develop new approaches to preventing the damage, scientists must first understand how amyloid-beta forms the telltale clumps. University of Michigan researchers have developed new molecular tools that can be used to investigate the process. The molecules also hold promise in Alzheimer's disease treatment. The research, led by assistant professor Mi Hee Lim, was published online this week in the Journal of the American Chemical Society. [Read more...]
Whooping cough immunity long-lasting, study shows
Immunity to whooping cough lasts at least 30 years on average, much longer than previously thought, an analysis by researchers at the University of Michigan and the University of New Mexico shows. The research, by U-M professor of ecology and evolutionary biology Pejman Rohani and his former postdoctoral fellow Helen Wearing, now an assistant professor at the University of New Mexico, is scheduled to be published Oct. 23, 2009 in the open-access journal PLoS Pathogens. Once thought to be under control, thanks to widespread childhood vaccination, whooping cough (pertussis) has been on the rise since the 1980s in the United States and several other countries. This increase has fueled concerns about the effectiveness of current vaccination practices and raised the question of whether whooping cough can ever be eradicated. [Read more...]

Underwater Archaeology
Exploring the bottom of Lake Huron for signs of ancient human life
The bottom of Lake Huron is filled with more than shipwrecks—there are also clues left behind from ancient man. LSA Professor of Anthropology John O’Shea found archaeological evidence of a 9,000-year-old hunting culture in the depths of Lake Huron, in collaboration with U-M Professor Guy R. Meadows, Director of U-M’s Marine Hydrodynamics Laboratories. [Read more...]

Muddy Waters
In the Fall 2009 issue of LSA Magazine, three experts from the College of Literature, Science & the Arts weigh in on the greatest threats facing the Great Lakes, and what can be done about the damage humans have inflicted (and continue to inflict) on the world's largest freshwater resource. [Read more...]

Color differences within and between species have common genetic origin
Spend a little time people-watching at the beach and you're bound to notice differences in the amount, thickness and color of people's body hair. Then head to the zoo and compare people to chimps, our closest living relatives. The body hair difference is even more pronounced between the two species than within our own species. Do the same genes cause both types of variation? Biologists have puzzled over that question for some time, not just with respect to people, chimps and body hair, but for all sorts of traits that differ within and between species. Now, a study by University of Michigan researchers shows that, at least for body color in fruit flies, the two kinds of variation have a common genetic basis. The research, led by evolutionary biologist Patricia Wittkopp, appears in the Oct. 23, 2009 issue of the journal Science.

Zell Lurie Institute awards student entrepreneurs more than $50,000 in grants
The Samuel Zell & Robert H. Lurie Institute for Entrepreneurial Studies at the Stephen M. Ross School of Business has announced the recipients of the Fall 2009 Eugene Applebaum Dare to Dream Grant Program, where students apply for funding to advance their innovative, high-potential business concepts toward launch. The 30 grant recipients submitted projects that range from a light sport aircraft design and manufacturing firm to an online fundraising platform for performers to a stationary bicycle that generates electricity. [Read more...]

Looking for common factors in tissue regeneration
Biologists long have marveled at the ability of some animals to re-grow lost body parts. Newts, for example, can lose a leg and grow a new one identical to the original. Zebrafish can re-grow fins. Using zebrafish as a model, researchers at the University of Michigan have found that some of the same genes underlie the process in different types of tissues. Genes involved in fin regeneration and heart repair are also required for rebuilding damaged light receptors in the eye, they found, suggesting that a common molecular mechanism guides the process, no matter what body part is damaged. [Read more...]

Physics professor awarded 2010 APS Frank Isakson Prize
Duncan Steel, Robert J. Hiller Professor of Engineering in the Department of Electrical Engineering and Computer Science, Professor of Physics, Professor of Biophysics, and Research Professor in the Institute of Gerontology, was awarded the 2010 Frank Isakson Prize for Optical Effects in Solids from the American Physical Society. Prof. Steel received this award, "For seminal contributions to nonlinear optical spectroscopy and coherent control of semiconductor heterostructures." His research has focused on the development and application of various laser-matter interaction studies and quantum optics in fields including plasmas, optical phase conjugation, atomic and molecular spectroscopy, condensed matter physics, protein folding and quantum computing. [Read more...]
